SELF-RENEWAL OF COLONY FORMING UNITS (CFU) IN SERIAL BONE MARROW TRANSPLANTATION EXPERIMENTS
نویسندگان
چکیده
منابع مشابه
Assay of Colony Forming Units in Culture (cfu-c)
The colony forming units in culture (cfu-c) in bone marrowcells, which were suppressed by immunosuppressive factor obtained from the serum of sarcoma 180 tumor bearing mouse, was restored to normal level by the addition of FR-900490in vitro. Furthermore, in mitomycin C (MMC)-treated mice the subsequent administration of FR-900490caused a significant increase of cfu-c in bone marrow cells depres...
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The bone marrow stromal cell population is comprised of fibroblasts, endothellal cells, fat cells and “reticular cells.” The characteristics and the regulatory role in hematopolesis of each of these cell types are unknown. A liquid culture system has been used to clone and to characterize human bone marrow fibroblast colony-forming cells (CFU-F). The linear relationship between the number of ce...
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Histologic study of locally curetted bone marrow showed a sequence of blood clot formation, displacement of the clot by a primitive reticular tissue, and hematopoietic regeneration. Histologic regeneration of sinusoidal vessels, and recovery was incomplete 12 wk later with increased fat, residual trabecular bone, and cystic areas. Recovery of colony-forming units (CFU) paralleled hematopoietic ...
متن کاملProduction of T lymphocyte colony-forming units from precursors in human long-term bone marrow cultures.
T cell differentiation in human marrow was studied in Dexter type long-term bone marrow cultures. In these cultures, T lymphocyte colony-forming units (TL-CFU), E rosette-forming cells (E+), and T3+, T4+, and T8+ cells (assayed by indirect immunofluorescence) were found to be present for at least 7 weeks. It was investigated whether the existence of T cells in long-term culture resulted from th...
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Eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (BMT) from HLA-matched siblings during the period of 1990 to 1996. The conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. Antilymphocyte globulin (ALG) and cyclosporine were used for rejection and acute GVHD prophylaxis, respe...
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ژورنال
عنوان ژورنال: Cell Proliferation
سال: 1972
ISSN: 0960-7722,1365-2184
DOI: 10.1111/j.1365-2184.1972.tb00376.x